Nancy Birdsall, our founding president, delivers the 2016 Richard Sabot Memorial Lecture, entitled "New Development Realities in a changing Global Order," in her last public event as CGD president. The same globalization that has brought benefits to millions of people in the developing world is seen as not working for many in advanced economies. Yet, despite today’s turbulent politics, globalization is unlikely to be going away. The question for politicians as well as for development economists is how do we make globalization work for people everywhere? What new development realities should shape our approach to that question?